服務熱線
15201163601
-
解析Iduron糖胺聚糖的一般生物學作用
發(fā)布時間： 2022-01-20 點擊次數(shù)： 1262次Iduron糖胺聚糖是長線性多糖，由重復的二糖單元（即兩個糖單元）組成。重復的二糖單元由一個糖醛糖和一個氨基糖組成，但角質(zhì)素除外，在該蛋白中，糖醛酸是半乳糖。由于GAG具有高極性并吸引水，因此它們在體內(nèi)用作潤滑劑或減震器。它的生產(chǎn)：Iduron糖胺聚糖的分子量，二糖結(jié)構(gòu)硫酸化差異很大。這是因為GAG合成不是像蛋白質(zhì)或核酸那樣由模板驅(qū)動，而是通過加工酶不斷地改變。基于核心二糖結(jié)構(gòu)，GAG分為四類。肝素/硫酸乙酰肝素（HSGAGs）和硫酸軟骨素/硫酸皮膚素（CSGAGs）是在高爾基體中合成的，其中粗糙的內(nèi)質(zhì)網(wǎng)中形成的蛋白質(zhì)核心被O-糖基化后的糖基轉(zhuǎn)移酶通過糖基轉(zhuǎn)移酶形成蛋白聚糖而被修飾。硫酸角質(zhì)素可以通過蛋白聚糖的N-聯(lián)糖基化或O-聯(lián)糖基化來修飾核心蛋白。GAG的第四類，透明質(zhì)酸 通過完整的膜合酶合成β-內(nèi)酰胺酶，該酶立即分泌動態(tài)拉長的二糖鏈。Iduron糖胺聚糖的一般生物學作用：1、由于糖胺聚糖的親水性強，對保持疏松結(jié)締組織中的水分有重要意義；2、糖胺聚糖是多價陰離子，對K+、Na+、Ca2+、Mg2+等有較大的親和力，因此能調(diào)節(jié)這些離子在組織中的分布；3、糖胺聚糖，主要是透明質(zhì)酸有很大的粘滯性，附在關(guān)節(jié)面上具有潤滑和保護作用；4、有促進創(chuàng)傷愈合的作用。
產(chǎn)品中心
Products
-
化學試劑
Origene parkell pan-biotech PAN lexogen Lampire labtidebiotech laborator labome ABI enzolifesciences emsdiasum EtonBioscience Equitech-bio kirgen invivogen integralmolecular Instech IndoorBiotechnologies INCELL IMMUSMOL G-Biosciences IMMUNOLOGICALS idtdna IMMUNODX ILLUMINA Immunodiagnostics IBALifeSciences Hypoxyprobe Horizon Cygnus Technologies Hellobio Greiner Cell Signaling Glycobiotech Corning FST Evrogen eurofins BioFire Defense biodatacorp atlasantibodies ATCC Astartebio ArcticZymes aobious anshlabs Advanced ChemTech Advaced Cell Diagnostics AdvanDx Agar Scientific ACBR TRc polyscience Fluka Gene Bridges fortebio Biocrick Fisher bioflux biomax beckman AmericanElements MOLTOX Permagen USA Scientific Chemgenes寡核苷酸 Asuragen vmrd抗體 Thermo asusragen AmplideX toxin polyplus signagen Berry&Associates ALZET滲透泵 alzet abcr abvector SGI-DNA Goldbio Iduron Sgidna Chromsystems Coriell GE Chemgenes Matreya Streck VMRD Sigma Cerilliant Innovative Cell Technologies Diagenode Trilinkbiotech Medkoo life diagnostics Gibco Neuromab全國總代 Novus BioLegend Bethyl Toxin Technology Listlabs Seracare 寶利嘉 賽默飛 安迪生物 行業(yè)專用試劑
-
生物試劑
Biosharp Sciex Seahorse Proteintech DiaMag complementtech PeproTech hooke Nzytech Pierce pepnet pelfreez PALL ozbiosciences OXOID ORFLO ommscientific omega nanopore ncbi NexcelomBioscience Mpbio MultiSciences MyBioSource Musechem MiltenyiBiotec minerva-biolabs microspheres-nanospheres microfil microbix modiquestresearch MOBITEC mercodia merckmillipore medicago JPT kerafast Kangchen Malvern magen Kapa Macrocyclics Macherey mabtech Lucigen leica Lifespan lifesensors lifeline life-ilab Lifecore life Licor advancedchemtech Affinity Abgent Abmgood ActiveMotif Acros Acrobiosystems enzymatics epicypher Elastin elabscience Echelon eBioscience eastcoast eaglebio E&K SCIENTIFIC ekfusa duran DSHB Dharmacon DGRC Dako Cypex comptech Encorbio Jetbiofil JCRBcellbank ISOSCIENCES INVIVOCHEM iris-biotech Full Moon BioSystems GBI FormnMax Finescience Favorgen CordenPharma CIL Chromadex Clodronateliposomes Chromogenix Chiron chemservice cellvis cellutron CELLTREAT cellscript cellbiolabs cellecta cedarlane cdnisotopes carbosynth cambio calbioreagents Buchem Boston Cellron Bioworld Biowest Biotium biostatus BiosPacific Biosearch BIOplastics Biooscientific BioPAL Biomol BIOMED Biomatik bioline Biocoat Bioclone Biocision biochain華新康信 biocell Biocare BIAseparations BDpharmingen Baseclick Badrilla B2S Life Sciences Axon Medchem AXIS-SHIELD avivasysbio avidity AVES-LABS Anatrace Americanbio AlphaDiagnoesticInternational Applied Genetics Laboratories Alstem Alomone AcceGen Akina AdvancedBioMatriX Adipogen Accuratechemical Academybiomed Abcam Zymo Research Addexbio ABL Abbexa Aablocks ZeptoMetrix Tocris TAKARA Spherotech Santa Roche Nist PBL MRC Holland rd-biotech Cellgs LC-LAB Greatcell Energy Hyclone Greerlabs GlycoSyn GlycoTech EY laboratories Cayman CanSyn Bioxcell Bio－Rad Agdia Abclonal amsbio auditmicro avantilipids Alsachim HTDialysis jetPRIME Carna Biosciences FItzgerald